This paper studies the disturbance-observer-based adaptive neural network cooperative event-triggered control problem for six-rotor unmanned aerial vehicles with finite-time prescribed performance. Six-rotor unmanned aerial vehicle systems are divided into the position subsystem and the attitude subsystem. The switching threshold event-triggered mechanism that considers the influence of event triggering on the consensus control performance is designed of each six-rotor unmanned aerial vehicle to save the transmission resources, which excludes the Zeno behavior. Neural networks are introduced for estimating the uncertainties and solving the algebraic loop problem. In addition, for the position subsystem, by combining the prescribed performance with the velocity function, a finite-time control scheme is proposed, which can guarantee that the consensus errors converge to a prespecified neighborhood of the origin, and all closed-loop signals are bounded. Based on the designed control input signal of position subsystem, an adaptive neural network event-triggered control mechanism is designed to stabilize the attitude subsystem. Finally, some verification results are given to test the rationality of the proposed control strategy. —The purpose of this paper is to design an event-triggered cooperative control scheme to save the transmission resources for six-rotor unmanned aerial vehicle systems with performance limitations and lumped disturbances. In practical applications, if the impact of the event-triggered mechanism on the system performance is not taken into account, the system performance may be significantly degraded while the information transmission resource is saved. Thus, this paper designs an event-triggered mechanism that considers the system performance, which can effectively weigh the relationship between system performance and transmission resource consumption and better meet the practical requirements. Moreover, a finite-time specified performance control strategy is introduced to avoid the problem of difficult determination of residual set and improve the transient-state and steady-state performances of unmanned aerial vehicle systems, which is more in line with the actual demand.