This paper proposes a novel robust tracking control scheme for discrete time linear uncertain Multiple-Input Multiple-Output (MIMO) systems subject to time-varying delay on the states. The considered system is affected by unknown but norm bounded uncertainties on parameters as well as matched disturbances on the states. The designed controller is based upon a proposed novel integral sliding surface and a new switching type of reaching law. Sufficient conditions based on Linear Matrix Inequalities (LMIs) and a suitable Lyapunov–Krasovskii Functional (LKF) are derived in order to guarantee the asymptotic stability of such system. The proposed controller ensures a good tracking performance despite the presence of the time varying delay and the matched/unmatched disturbances. Moreover and thanks to the proposed integral surface, the time reaching phase is eliminated and the chattering phenomenon is significantly reduced. The proposed controller is applied on an Autonomous Underwater Vehicle (AUV) to follow a prescribed desired trajectory. The simulation results illustrate the effectiveness of such controller.